Elske Hoornenborg of the Public Health Service Amsterdam with her poster presentation at CROI 2017 in Seattle
By: Ben Ryan
A Dutch man has contracted a non-drug-resistant strain of HIV while, according to numerous sources of evidence, adhering well to the daily regimen of Truvada (tenofovir disoproxil fumarate/emtricitabine) as pre-exposure prophylaxis (PrEP). His case has puzzled experts because the only two cases of PrEP failure documented thus far, both reported within the past year, involved rare drug-resistant strains of the virus that apparently evaded the two drugs in Truvada.
Researchers are able only to speculate as to how this man could have contracted HIV. They theorize that his “remarkably high” number of sex partners and condomless sex episodes may have contributed to this aberrant outcome.
Elske Hoornenborg, MD, an infectious disease specialist the Public Health Service Amsterdam presented findings from the case study in a poster presentation at the 2017 Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle.
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