A study in the Journal of Infectious Diseases found that men with high-risk sexual behavior and a history of the human papillomavirus (HPV) are at an increased risk for the recurrence of the viral infection, particularly for the HPV types found in the newly approved nonavalent HPV vaccine (ie, HPV 6, 11, 16, 18, 31, 33, 45, 52, and 58). A higher number of new sexual partners, as well as lifetime sexual partners, may drive this risk in these patients.
“In the current analysis, higher numbers of new male sexual partners were consistently associated with higher recurrence of incident infections in both type-specific (HPV 16) and grouped analyses,” according to the study investigators led by Anna R. Giuliano, PhD, director of the Center for Infection Research in Cancer at the Moffitt Cancer Center. “Other high-risk sexual behaviors (number of new female partners and frequency of sexual intercourse) were also associated with higher recurrence of prevalent HPV 6, 16, and 31 infections. Recurrence significantly differed by smoking and alcohol use only for HPV types 16, 52, and 58.”
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