A recent study to compare the efficacy of pritelivir with valacyclovir for suppression of genital HSV-2 infection has been released by the Journal of the American Medical Association.
Question Is pritelivir more effective than valacyclovir for suppression of genital herpes simplex virus 2 (HSV-2) shedding in patients with frequent recurrences?
Findings In this double-blind, randomized crossover study of 91 adults with recurrent genital herpes, the percentage of genital swabs with HSV detected over 28 days was significantly lower during use of pritelivir than use of valacyclovir (2.4% vs 5.3%).
Meaning Pritelivir may be more effective for suppression of genital HSV-2 infection than valacyclovir, but further research is needed to assess longer-term efficacy and safety.
To read the full abstract please click here.